منابع مشابه
Spare hypoxia, spoil the child?
Current knowledge The patient in this scenario illustrates a common and increasingly frequent clinical scenario in pediatric hospitals and wards. The most recent published admissions data from The Pediatric Health Information System database show that children with significant chronic medical conditions accounted for 19.2% of hospitalized patients, but a remarkable 48.9% of hospital days and 53...
متن کاملSpare the Rod1, spoil transporter endocytosis
W hen the waitress brings you soup in a restaurant, you put down your fork and pick up a spoon. Cells do something similar when they change their diet, switching the nutrient-importing proteins in their plasma membrane. Becuwe et al. show how the post-translational modifi cation of a key adaptor protein enables cells to remove unneeded transporters (1). Transporter proteins embedded in the plas...
متن کاملSpare the rod, spoil the degeneration.
A host of retinal degenerations, including many types of retinitis pigmentosa, follow a pattern of rod loss followed by cone loss. The rod loss may take many years, causing problems with night vision and peripheral visual field constriction. Only after significant rod loss occurs does cone loss ensue, with its devastating loss of central vision. The pathophysiology for some of these degeneratio...
متن کاملSpare the Mbl, spoil the rod?
Fibronectin for branching ranched organs are shaped when epithelia make their own paths, according to a study by Takayoshi Sakai, Melinda Larsen, and Kenneth Yamada (National Institutes of Health, Bethesda, MD). The pathmaker in this process is fibronectin (FN), which tells cells to let go of their neighbors and instead grab hold of the underlying matrix. Organs such as the lung and kidney gain...
متن کاملMotor Learning: Spare the Rod to Benefit the Child?
A new study has found that individuals who were rewarded while they learned a motor task performed it much better one month later than those who were punished or received nothing. Long-term memories depend on events experienced during learning.
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2015
ISSN: 0021-9738
DOI: 10.1172/jci80820